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This list is not complete and there may be other drugs that can interact with clozapine. Do not start using new medication without telling your doctor. If desired, you may drink liquid to help swallow the dissolved tablet. Use with caution in sconto clozapine patients at risk of seizures, including those with history of seizures, head trauma, brain damage, alcoholism, or concurrent therapy with medications which may lower seizure threshold. As with any antipsychotic drug, chronic Clozapine use should be reserved for patients who appear to be obtaining substantial benefit from the drug. Clozapine may raise your blood sugar, causing symptoms such as increased thirst, loss of appetite, increased urination, drowsiness, nausea, or fruity breath odor. It is well known that drugs bound to plasma proteins are not only the portion of the drug that is not bound to the protein is available to do whatever it is that the drug is supposed to do.