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USES: Etodolac is used to relieve pain from various conditions. On chronic dosing, hydroxylated-etodolac metabolite does not accumulate etodolac-tabletter in the plasma of patients with normal renal function. Or if abnormal liver tests persist or worsen, etodolac extended-release tablets should be discontinued. The diuretic effect of furosemidemay be reduced with concurrent etodolac and digoxin heart medicine may achieve higher than normal blood levels. These were observed at dose levels to 14 mg kg day close to human clinical doses.