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Patients should be cautioned about the risk of serotonin syndrome with the use of sumatriptan or other triptans, especially during combined use with SSRIs or SNRIs. Special Populations Renal Impairment: The effect of renal impairment on the pharmacokinetics of sumatriptan has not been examined, but little clinical effect would be expected as sumatriptan is largely metabolized to an inactive substance. May it also be nasal congestion on the affected side of the face. Second dose of IMITREX Tablets or other medication was allowed to 24 hours after sumatriptan apotheke the initial treatment for recurrent headache. Oral Dosage Forms Note: Sumatriptan tablets contain sumatriptan succinate.
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